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Corrosive esophagitis in children
Yu-Chih Huang1, Yen-Hsuan Ni, Hong-Shiee Lai
1Department of Pediatrics, National Taiwan University Hospital, No. 7 Chung-Shan South Road, 100 Taipei, Taiwan.
Insights
Accidental ingestion of alkaline oil is a common cause of corrosive esophagitis in children. Severe esophageal burns correlate with stricture formation, impacting recovery and requiring interventions like dilatation or surgery.
Area of Science:
- Pediatric Gastroenterology
- Toxicology
- Otolaryngology
Background:
- Corrosive esophagitis in children poses significant management challenges.
- Accidental ingestion is the primary cause, with alkaline substances being particularly dangerous.
- The long-term outcomes and optimal treatment strategies require further elucidation.
Purpose of the Study:
- To evaluate the outcomes of corrosive esophagitis in pediatric patients.
- To identify the most common causative agents and risk factors.
- To determine the optimal management strategies for esophageal strictures.
Main Methods:
- Retrospective analysis of 24 pediatric patients treated for corrosive esophagitis between 1984 and 2001.
- Classification of ingested substances (alkali, acid, neutral) and assessment of burn severity.
- Evaluation of treatment modalities including endoscopic dilatation and surgical interventions.
Main Results:
- Alkali ingestion, particularly "dumpling alkaline oil," was the most frequent cause (71%).
- Esophageal strictures developed in 15 of 21 patients with esophageal injury, correlating with burn degree.
- Patients with strictures experienced poorer functional recovery, including feeding difficulties and growth retardation.
Conclusions:
- Accidental ingestion of alkaline oil is a leading cause of pediatric corrosive esophagitis in Taiwan.
- The severity of esophageal burns directly correlates with the risk of stricture formation.
- Timely intervention, including endoscopic dilatation and surgery, is crucial for managing strictures and improving patient outcomes.
Abstract:
We evaluated the outcome and optimal management of corrosive esophagitis in 24 children (male:female=8:16, mean age 5.0+/-5.4 years old, ranged from 15 months to 18 years of age) from January 1984 to July 2001. In 20 patients this was the result of accidental ingestion, 4 were suicide attempts and 15 patients (63%) were below 3 years of age. The ingested substances included alkali (n=17, 71%), acid (n=6, 25%), and neutral detergent (n=1, 4%). The "dumpling alkaline oil", a traditional food additive used in Taiwan, was the most common culprit in this study. A total of 9 patients ingested the dumpling alkaline oils, which comprised 38% of the total 24 patients and 53% of the 17 alkaline ingestion accidents. Of the patients 21 (88%) suffered from esophageal injury, and 15 among these 21 patients developed esophageal strictures. Esophageal strictures occurred in all patients with second or third-degree burns. Of these 15 patients with esophageal strictures, 9 (60%) received endoscope-associated dilatation and 6 (40%) underwent an operation (esophagectomy and intestinal interposition). The 9 patients who did not develop esophageal strictures had good body weight gain without feeding difficulty (functionally normal recovery). On the other hand, among the 15 patients with esophageal strictures, 9 patients had functionally subnormal recovery and 6 patients had poor recovery with either frequent feeding difficulty or growth retardation. In conclusion, accidental ingestion of alkaline oil is the most common cause of corrosive esophagitis in Taiwan. The degree of burns correlated with stricture formation.
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