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Related Experiment Videos

Chorionic villus sampling in Auckland 1989-90.

M Birdsall1, A B Roberts, R Fisher

  • 1Department of Obstetrics, Auckland University School of Medicine, National Women's Hospital.

The New Zealand Medical Journal
|August 26, 1992
PubMed
Summary

This audit of chorionic villus sampling (CVS) in Auckland found a fetal loss rate lower than multicenter trials. However, initial sampling success rates were poor, improving over time.

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Area of Science:

  • Obstetrics and Gynecology
  • Prenatal Diagnosis
  • Fetal Medicine

Background:

  • Chorionic villus sampling (CVS) is a key prenatal diagnostic tool.
  • Auditing local procedures is essential for quality improvement.

Purpose of the Study:

  • To audit chorionic villus sampling (CVS) procedures performed in Auckland between 1989-1990.
  • To assess fetal loss rates and procedural success.

Main Methods:

  • Audit of 197 chorionic villus sampling (CVS) procedures.
  • Outcome tracing in 188 of 197 cases.
  • Analysis of procedural methods (transvaginal vs. transabdominal).

Main Results:

  • 89% of CVS procedures were transvaginal; 11% transabdominal.

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  • Overall fetal loss rate was 9.6%, with a spontaneous loss rate of 4.3%.
  • Initial sampling failure rate was 13.7%, improving to 10% in the second year.
  • Conclusions:

    • The fetal loss rate was comparable to or lower than reported multicenter trials.
    • Initial sampling success rates were suboptimal but improved with experience.
    • No procedural failures resulted in failed cultures or mosaicism.