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Updated: Aug 24, 2026

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
Published on: October 10, 2025
Solitary neurofibroma of the spermatic cord
Konstantinos N Milathianakis1, Dimitrios K Karamanolakis, Ioannis M Mpogdanos
1Department of Urology, Anticancer Hospital of Piraeus-Metaxa, Piraeus, Greece.
Abstract:
Neurofibromas, which arise from perineural and Schwann cells, commonly occur throughout the body, but they rarely have been reported to originate from the spermatic cord. The solitary neurofibroma is a localized tumour that, by definition, occurs in patients who do not have von Recklinghausen's disease. Its exact incidence is unknown because of the difficulty in excluding von Recklinghausen's disease in some cases. Leiomyomas, lipomas, fibromas, haemangiomas, and epidermoid cysts have been described as benign tumours of the scrotum, but rarely has an extratesticular solitary neurofibroma of the spermatic cord been reported. We report a case of a solitary neurofibroma arising from the left spermatic cord. No signs of von Recklinghausen's disease were identified.
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