Intraoperative Arthroscopic Cold Irrigation Solution Does Not Affect Postoperative Pain and Swelling
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Updated: Aug 24, 2026

Knee Arthrocentesis in Adults
Published on: February 25, 2022
A Louise Fincher1, G William Woods, Daniel P. O'Connor
1University of Texas at Arlington, Arlington, TX.
Abstract:
OBJECTIVE: To determine what effect using a cold irrigating solution during arthroscopic knee surgery would have on postoperative pain intensity, pain-medicine consumption, and knee joint swelling. DESIGN AND SETTING: We employed a randomized, controlled trial design. Subjects were randomly assigned to either the cold (4 degrees C) irrigating saline group or room-temperature (18 degrees C) irrigating saline (control) group. Subjects were blinded to group assignment. All surgeries were performed at the same hospital by the same surgeon. SUBJECTS: The sample was 93 physically active patients (32 women, 61 men, mean age = 47.4 +/- 15.1 years) who had knee injuries requiring surgery. Those with cold sensitivities or contraindications to the use of cold were excluded. MEASUREMENTS: A 10-cm horizontal visual analog scale was used to measure postoperative pain intensity. Postoperative pain-medicine consumption was recorded using a daily log. Knee joint swelling (girth) was measured at midpatella and 2 in (5.08 cm) above midpatella. Pain and swelling measures were collected before and after surgery. RESULTS: No statistical or clinical differences were found between the cold-saline and control groups for pain, pain-medicine consumption, and postoperative swelling across the first 4 postoperative days. CONCLUSIONS: Our results suggest that using intra-articular cold saline to irrigate the knee joint during arthroscopic surgery had no statistically or clinically significant effect on postoperative pain, medication usage, or swelling in the first 4 postoperative days.
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