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Related Experiment Videos

Signal-averaged electrocardiography in normal newborn infants.

R G Bennhagen1, L Sörnmo, O Pahlm

  • 1Division of Paediatric Cardiology, Department of Paediatrics, Lund University Hospital, S-221 85, Lund, Sweden.

Pediatric Cardiology
|April 16, 2004
PubMed
Summary

Signal-averaged electrocardiograms (SAECGs) in newborns show that the QRS duration upper limit is 100 ms. Standard 12-lead ECGs offer practical advantages for SAECG analysis in infants.

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Area of Science:

  • Neonatal cardiology
  • Electrophysiology
  • Pediatric diagnostics

Background:

  • Signal-averaged electrocardiograms (SAECGs) are crucial for assessing ventricular arrhythmias.
  • Establishing normal SAECG parameters in newborns is essential for early detection of cardiac abnormalities.
  • Comparing different lead configurations for SAECG in neonates is necessary to optimize diagnostic utility.

Purpose of the Study:

  • To determine the normal range for QRS duration in healthy newborn infants using SAECGs.
  • To compare the efficacy and practicality of bipolar orthogonal versus standard 12-lead ECG configurations for neonatal SAECG.
  • To evaluate the suitability of specific SAECG parameters (QRSD, RMS40) in newborns.

Main Methods:

  • Signal-averaged electrocardiograms (SAECGs) were recorded in 29 healthy term newborns.

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  • Two lead configurations were used: bipolar orthogonal and standard 12-lead.
  • Analysis focused on QRS duration (QRSD) and root-mean-square voltage (RMS40).

    • Main Results:

    • The upper limit of normal for QRS duration (QRSD) in newborns was established at 100 ms.
    • Both lead configurations yielded comparable quality and quantity of SAECG data.
    • RMS40 in individual leads was highly variable and not a suitable discriminant variable for newborns.
    • Reference values for RMS40 and low-amplitude signal duration in vectorcardiograms (VM) are similar to adults.

    Conclusions:

    • The standard 12-lead ECG configuration is practical and advantageous for neonatal SAECG due to its widespread use.
    • Individual lead recordings offer complementary information to vectorcardiograms.
    • The established QRSD limit of 100 ms is reliable for assessing newborn cardiac electrical activity.