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[Resistance phenotypes circulating in nosocomial high risk departments]
Monica Licker1, Roxana Moldovan, Luminiţa Bădiţoiu
1Catedra de Microbiologie, UMF Victor Babeş Timişoara.
Objectives:
Between November 2001-January 2002 we collected 406 samples from patients hospitalized in Intensive Care adults and new-borns Unit (ICU). The aim was to observe the colonization and infection status with bacteria that may have nosocomial potential and to establish circulating phenotypes in ICUs.
Methods:
The identification was performed by API (bioMerieux) method, and we have performed the antimicrobial susceptibility tests by both: API method and by Kirby-Bauer disc-diffusion test.
Results:
We isolated 295 strains with nosocomial potential: 34 MRSA strains, 23 MRCNS strains, 29 ESBL producing gram negative rods, etc.
Conclusions:
We observed the presence of multiple drug resistant bacteria which play an important roll in both: massive colonization of patients and in the etiology of nosocomial infections. This leads us to the conclusion that antibiotic resistance pattern should be interpreted by the bacteriologist and a consistent policy concerning the use of antimicrobial drugs in hospital settings should be instituted.
Insights
This study identified multiple drug-resistant bacteria in Intensive Care Units (ICUs), highlighting their role in patient colonization and nosocomial infections. Findings emphasize the need for expert interpretation of antibiotic resistance patterns and consistent hospital antimicrobial policies.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Hospital Epidemiology
Background:
- Nosocomial infections pose a significant threat in Intensive Care Units (ICUs).
- Understanding bacterial colonization and infection patterns is crucial for effective patient management.
- Identifying circulating bacterial phenotypes in ICUs aids in infection control strategies.
Purpose of the Study:
- To assess bacterial colonization and infection in hospitalized adult and newborn ICU patients.
- To identify bacteria with nosocomial potential.
- To determine the prevalent bacterial phenotypes within ICUs.
Main Methods:
- Collected 406 patient samples from November 2001 to January 2002.
- Utilized API (bioMerieux) for bacterial identification.
- Performed antimicrobial susceptibility testing using API and Kirby-Bauer disc-diffusion methods.
Main Results:
- Isolated 295 bacterial strains with nosocomial potential.
- Identified 34 Methicillin-resistant Staphylococcus aureus (MRSA) strains.
- Detected 23 Methicillin-resistant Coagulase-Negative Staphylococcus (MRCNS) strains and 29 ESBL-producing gram-negative rods.
Conclusions:
- Observed widespread presence of multidrug-resistant bacteria in ICUs.
- Confirmed the significant role of these bacteria in patient colonization and nosocomial infections.
- Recommended bacteriologist interpretation of antibiotic resistance and consistent hospital antimicrobial policies.
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