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Distribution of synchronous and metachronous multiple colorectal cancers
Yoichi Ikeda1, Motonori Saku, Hirofumi Kawanaka
1Department of Surgery and Clinical Research Institute, National Kyushu Medical Center, Fukuoka, Japan. yoikeda@qmed.hosp.go.jp
Background/Aims:
Synchronous and metachronous multiple colorectal cancers are not rare occurrences. Since features of colorectal cancer depend on tumor location, we focused attention on the tumor distribution of synchronous and meta-chronous lesions in colorectal cancer.
Methodology:
The records of 1812 patients with colorectal malignancies (either invasive colorectal cancer or high grade dysplasia) were clinicopathologically analyzed.
Results:
In one hundred and twenty patients with colorectal malignancies there were synchronous or metachronous lesions. The distribution of synchronous malignancies showed a significant shift from the proximal to the distal site, while in metachronous malignancies, the distribution of second tumors showed a significant shift from the distal to the proximal site.
Conclusions:
Our findings suggest that different types of cancer lesions do exist, hence careful and meticulous examinations are important.
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