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Psychiatric medication-induced obesity: a review.
T L Schwartz1, N Nihalani, S Jindal
1SUNY Upstate Medical University, Department of Psychiatry, Syracuse, NY 13210, USA. schwartzresearch1@yahoo.com
Summary
Psychiatric medications like antidepressants and antipsychotics often cause significant weight gain, leading to serious health issues. Research is exploring the causes and treatments for this common side effect.
Area of Science:
- Psychiatry
- Endocrinology
- Pharmacology
Background:
- Weight gain is a prevalent side effect of many psychiatric medications.
- This weight gain can lead to obesity and associated comorbidities.
- Understanding the epidemiology and etiology of this side effect is crucial.
Purpose of the Study:
- To review the existing literature on psychotropic-induced weight gain.
- To explore the prevalence, causes, and treatment options for medication-induced weight gain.
- To highlight the long-term health implications of this side effect.
Main Methods:
- Comprehensive literature search of relevant studies.
- Analysis of data on weight gain associated with various psychiatric drug classes.
- Review of emerging treatments for managing psychotropic-induced weight gain.
Main Results:
- Mood stabilizers, antipsychotics, and antidepressants are frequently associated with weight gain.
- Few psychotropic medications are weight-neutral or promote weight loss.
- Weight gain can precipitate secondary health problems like hypertension and diabetes.
Conclusions:
- Psychotropic-induced weight gain is a significant clinical concern with long-term health consequences.
- Further research into the etiology and effective management strategies is warranted.
- Clinicians should consider weight management when prescribing psychiatric medications.