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Published on: April 12, 2021
Long-term social outcome of children after kidney transplantation
Michel Broyer1, Christine Le Bihan, Marina Charbit
1Department of Pediatric Nephrology, and Hôpital Necker Enfants Malades and University Paris V René Descartes, Paris, France. michel.broyer@nck.ap-hop-paris.fr.
Insights
Adult social outcomes for childhood kidney transplant recipients are encouraging, with most patients achieving good employment and independent living. Achieving normal adult height is significantly linked to better educational attainment and social integration.
Area of Science:
- Pediatric Nephrology
- Transplant Surgery
- Social Medicine
Background:
- Limited data exists on the long-term social outcomes of individuals who received kidney transplants during childhood.
- This study addresses this gap by examining a cohort of 366 pediatric kidney transplant recipients.
Purpose of the Study:
- To evaluate the adult social outcomes of children who underwent kidney transplantation between 1973 and 1985.
- To identify factors influencing social success in this population.
Main Methods:
- A questionnaire was administered to 244 former pediatric kidney transplant patients.
- Data collected included demographics, graft status, educational attainment, employment, marital status, parental status, living situation, and final height.
Main Results:
- At a mean age of 31.7 years, 77% had functioning grafts. Educational levels were below national averages, but employment rates were comparable. Women had higher rates of marriage and children than men. Independent living was achieved by 54%.
- Multivariate analysis revealed significant correlations between final height and educational level, paid employment, marital life, and independent housing.
Conclusions:
- The long-term social outcomes for individuals transplanted in childhood are generally positive.
- Attaining normal adult height is a crucial factor associated with improved social and educational achievements.
Background:
There are few data concerning the social outcome at adult age of children who received a kidney transplant. The aim of this study was to collect information on this outcome in a cohort of 366 children who underwent transplantation between 1973 and 1985.
Methods:
Information was obtained through a simple questionnaire in 244 patients. The mean age of the patients was 31.7 years, and they had undergone grafting at a mean age of 11.9 years.
Results:
As of December 2000 or at last visit, 77% had a functioning graft. The mean height was 156.6 cm for male patients and 147.4 cm for female patients. The distribution of educational level was lower than national averages: 27.4% were at the lowest level versus 3% of the general population, 41.4% were at the middle level, 31.2% had reached the baccalaureate level, and 11% had followed a university cursus. Activity was similar to the general population: 73% had paid employment versus 72%, 6.5% were unemployed versus 10.5%, and 18.7% received a disablement pension. Among the 149 male patients, 39 (27%) had a marital life and 12 (8.3%) had children, whereas among the 95 female patients, 48 (50%) had a marital life and 26 (27%) had at least one child. Lodging was the parent's home in 46% and independent in 54%. Multivariate analysis showed a significant correlation between educational level, paid activity, marital life, and independent housing with final height.
Conclusions:
The long-term social outcome of patients who underwent grafting in childhood more than 15 years previously is encouraging. The importance of reaching a normal height is stressed.
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