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A Modified Surgical Technique for Kidney Transplantation in Mice
Published on: July 22, 2022
Kidney transplantation into patients with abnormal bladders
1Division of Urology and Renal Transplantation, The Oregon Health and Science University, Portland, OR 97239, USA. barryj@ohsu.edu
Abstract:
An abnormal urinary bladder is no longer a contra-indication to renal transplantation. A normal urinary bladder stores urine at low pressure, does not leak, and empties completely by natural voiding. In contrast, an abnormal urinary bladder stores urine at high pressure, leaks, or does not empty completely by natural voiding. A variety of procedures have been devised to change the abnormal bladder into a continent low-pressure reservoir. Knowledge of these bladder modifications and their management should allow successful transplantation in patients with abnormal bladders and provide outcomes that match or approach those achieved in patients with a normal bladder.
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