Related Experiment Video
Updated: Jul 25, 2026

3D Kinematic Analysis for the Functional Evaluation in the Rat Model of Sciatic Nerve Crush Injury
Published on: February 12, 2020
Sciatic nerve blockade improves early postoperative analgesia after open repair of calcaneus fractures
J Cooper1, S Benirschke, B Sangeorzan
1Department of Anesthesiology, University of Washington School of Medicine, Harborview Medical Center, Seattle, WA, USA. JeremyCo@adhb.govt.nz
Objective:
To determine the effectiveness of analgesia, with or without sciatic nerve blockade, after open repair of calcaneus fracture.
Design:
Randomized, prospective trial involving 30 patients divided into 3 groups of 10, all having open repair of calcaneus fractures. Group 1 used morphine patient-controlled analgesia alone. Groups 2 and 3 had morphine patient-controlled analgesia and a "one-shot" bupivacaine sciatic nerve blockade, either presurgically (group 2) or postsurgically (group 3).
Setting:
Harborview Medical Center operating rooms and orthopedic floors.
Outcome Measures:
Morphine use over 24 hours, visual analogue scale pain scores, and sciatic nerve blockade duration.
Results:
In the absence of sciatic nerve blockade, initial postoperative pain was marked, even with a mean recovery room dose of intravenous morphine more than 30 mg. Sciatic nerve blockade with bupivacaine had a mean duration of 14 hours and substantially reduced pain for the first 24 postoperative hours. Presurgical blockade confers no advantage over postsurgical blockade.
Conclusion:
Sciatic nerve blockade confers significant benefit over morphine alone for analgesia after open repair of calcaneus fractures. Postsurgical sciatic nerve blockade provides the longest possible postoperative block duration.
Related Concept Videos
Local Anesthetics: Clinical Application as Spinal Anesthesia
Peripheral Artery Disease V: Postoperative Nursing Management

