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Related Experiment Videos

Disorders of sweating.

William P Cheshire1, Roy Freeman

  • 1Department of Neurology, Mayo Clinic, Jacksonville, Florida 32224, USA.

Seminars in Neurology
|April 17, 2004
PubMed
Summary
This summary is machine-generated.

Sweating disorders like hyperhidrosis (excess sweating) and hypohidrosis/anhidrosis (deficient sweating) require accurate diagnosis. Understanding the anatomical pattern and autonomic nervous system lesion is key for effective treatment.

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Area of Science:

  • Neurology
  • Dermatology
  • Physiology

Background:

  • Sweating disorders encompass sudomotor excess (hyperhidrosis) and deficiency (hypohidrosis/anhidrosis).
  • Hyperhidrosis involves sweating beyond thermoregulatory needs, while hypohidrosis/anhidrosis impairs evaporative heat loss.
  • Anhidrosis can lead to hyperthermia and may indicate serious underlying conditions.

Purpose of the Study:

  • To outline the clinical spectrum of sweating disorders.
  • To emphasize the diagnostic importance of anatomical sweating patterns and autonomic nervous system lesion localization.
  • To review current treatment modalities for hyperhidrosis.

Main Methods:

  • Clinical spectrum analysis of sweating disorders.
  • Autonomic nervous system lesion localization based on sudomotor deficits.

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  • Review of established treatments for hyperhidrosis.

    • Main Results:

    • Sudomotor deficits can affect various levels of the nervous system, including the brain, spinal cord, ganglia, and peripheral nerves.
    • Hyperhidrosis is typically benign, but anhidrosis poses a risk of hyperthermia.
    • Accurate diagnosis is crucial as sweating abnormalities can signal other disorders.

    Conclusions:

    • Diagnosis of sweating disorders necessitates identifying the sweating pattern and the specific autonomic nervous system lesion.
    • Treatment options for hyperhidrosis range from topical agents to surgical interventions.
    • Understanding the underlying cause is vital for managing both hyperhidrosis and hypohidrosis/anhidrosis.