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Updated: Aug 24, 2026

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
13:08

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay

Published on: September 9, 2012

[Myocardial infarction as an initial symptom of antiphospholipid syndrome, factor V Leiden mutation, and

Jerzy Dropiński1, Wojciech Wegrzyn, Wojciech Szczeklik

  • 1II Katedra Chorób Wewnetrznych CM UJ w Krakowie. j.dropinski@chello.pl

Polskie Archiwum Medycyny Wewnetrznej
|April 20, 2004
PubMed

We present a case of a 32-year-old male survivor of two myocardial infarctions, without any classic risk factor of atherosclerosis. Laboratory and genetic diagnostic tests revealed primary antiphospholipid syndrome, mutation in blood coagulation factor V (Leiden) and mild hyperhomocysteinemia, which could be predisposing factors for coronary artery occlusions and should especially be considered in a young patient without apparent cardiovascular risk factors. Additional anticoagulation and substitutional treatment of the folic acid, vitamin B6 and B12 are effective and the continues to do well at home 3 years after discharge.

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