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Modeling Myotonic Dystrophy 1 in C2C12 Myoblast Cells
09:39

Modeling Myotonic Dystrophy 1 in C2C12 Myoblast Cells

Published on: July 29, 2016

Genetic study of somatic mosaicism in a patient with myotonic dystrophy type 1: case report

V Rakocevic-Stojanovic1, D Savic, S Romac

  • 1Institute of Neurology, Clinical Center of Serbia, Belgrade. vidosava_r@yahoo.co.uk

Acta Myologica : Myopathies and Cardiomyopathies : Official Journal of the Mediterranean Society of Myology
|April 20, 2004
PubMed
Abstract

No abstract available in PubMed .

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Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...

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