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[Thalidomide: (re)discovery of a not very dear old molecule]
Albéric Bressoud1, Béatrice Zimmerli Schwab
1Service d'Oncologie Hôpital des Cadolles, 2000 Neuchâtel. alberic.bressoud@ne.ch
Revue Medicale De La Suisse Romande
|April 20, 2004
Abstract:
The angiogenesis is an early event in tumorigenesis. Angiogenesis inhibitors have been developed and are now studied in clinical trials. Angiogenesis research has induced a renewal of thalidomide. Thalidomide inhibits tumoral angiogenesis, allowing a good palliative treatment for hematological malignancies, especially for multiple myeloma and myelodysplastic syndromes.