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Indocyanine green angiography in high myopia
Ruth Axer-Siegel1, Daniel Cotlear, Ethan Priel
1Department of Ophthalmology, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Israel.
Summary
Confocal indocyanine green angiography better visualizes lacquer cracks and choroidal neovascularization (CNV) in pathologic myopia than fluorescein angiography. This advanced imaging technique aids in understanding these complex ocular conditions.
Area of Science:
- Ophthalmology
- Medical Imaging
- Retinal Diseases
Background:
- Pathologic myopia is associated with significant choroidal changes.
- Accurate imaging is crucial for diagnosing and managing complications like lacquer cracks and choroidal neovascularization (CNV).
Purpose of the Study:
- To evaluate indocyanine green (ICG) angiography for imaging choroidal changes in pathologic myopia.
- To compare the efficacy of ICG angiography with fluorescein angiography (FA) in this patient group.
Main Methods:
- Retrospective review of angiograms from patients with pathologic myopia.
- Utilized confocal indocyanine green angiography and fluorescein angiography for imaging.
Main Results:
- Indocyanine green angiography identified lacquer cracks in 89% of eyes, compared to 28% with FA.
- Choroidal neovascularization (CNV) detection rates were similar (57% ICG vs. 56% FA).
- ICG angiography delineated 70% of CNVs within lacquer cracks, identifying 124 cracks versus 14 with FA.
Conclusions:
- Confocal indocyanine green angiography provides superior delineation of lacquer cracks in pathologic myopia.
- ICG angiography offers better localization of choroidal neovascularization within lacquer cracks compared to fluorescein angiography.