Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Blood viscosity parameter correlation with types of leukemia.

K Sharma1, R R Puniyani, S V Bhat

  • 1School of Biomedical Engineering, Indian Institute of Technology, Powai, Bombay.

Physiological Chemistry and Physics and Medical NMR
|January 1, 1992
PubMed
Summary

This study reveals distinct hemorheological and hematological changes in acute lymphocytic leukemia (ALL), acute myelogenous leukemia (AML), and chronic myelogenous leukemia (CML). Red cell filterability remained unchanged across all leukemia types.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrative machine learning approaches with genomic data for predicting antitubercular drug resistance: A systematic review and meta-analysis.

Journal of global antimicrobial resistance·2025
Same author

A method to measure renal inner medullary perfusion using MR renography.

Magma (New York, N.Y.)·2025
Same author

Association of Waist Circumference and Body Mass Index among the Students of a Medical College.

Kathmandu University medical journal (KUMJ)·2024
Same author

The sensory shark: high-quality morphological, genomic and transcriptomic data for the small-spotted catshark <i>Scyliorhinus canicula</i> reveal the molecular bases of sensory organ evolution in jawed vertebrates.

bioRxiv : the preprint server for biology·2024
Same author

Cardio-oncology: Examination of progress in China from an oncologist's perspective.

Asia-Pacific journal of oncology nursing·2024
Same author

IGF-1 stabilizes goat sperm mitochondrial transmembrane potential and reduces dna fragmentation.

Cryo letters·2024

Area of Science:

  • Hematology
  • Oncology
  • Biochemistry

Background:

  • Leukemia, a cancer of blood-forming tissues, significantly impacts hematological and hemorheological parameters.
  • Understanding these alterations is crucial for diagnosis and management of different leukemia subtypes.

Purpose of the Study:

  • To investigate and compare hemorheological, hematological, and biochemical profiles in acute lymphocytic leukemia (ALL), acute myelogenous leukemia (AML), and chronic myelogenous leukemia (CML).

Main Methods:

  • Analysis of whole blood viscosity, plasma viscosity, erythrocyte sedimentation rate (ESR), red cell filterability, hematocrit, platelet count and aggregation, fibrinogen, hemoglobin, leucocyte count, bleeding time, and lactate dehydrogenase (LDH) activity.
  • Comparative study across 30 ALL, 21 AML, and 30 CML cases.

Related Experiment Videos

Main Results:

  • ALL cases showed decreased whole blood viscosity, hemoglobin, hematocrit, and platelet count, with increased plasma viscosity, fibrinogen, bleeding time, and LDH.
  • AML cases exhibited increased whole blood viscosity, plasma viscosity, ESR, fibrinogen, leucocyte count, bleeding time, and LDH, alongside decreased hemoglobin, hematocrit, and platelet count.
  • CML cases presented increased whole blood viscosity, plasma viscosity, ESR, and fibrinogen, with decreased bleeding time.
  • Red cell filterability was unaffected in all leukemia types.

Conclusions:

  • Distinct hemorheological and hematological patterns characterize ALL, AML, and CML.
  • These findings contribute to understanding the pathophysiology of different leukemia subtypes and may aid in clinical assessment.