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Updated: Aug 23, 2026

State of the Art Cranial Ultrasound Imaging in Neonates
Published on: February 2, 2015
[Characteristics of thyroid sonography in infants and children]
V Klingmüller1, C Fiedler, A Otten
1Röntgenabteilung Pädiatrie des Klinikums der Justus-Liebig Universität, Giessen.
Insights
Ultrasound reveals normal thyroid gland volumes in children, from neonates to adolescents. Abnormalities in thyroid structure were detected in various pediatric conditions, highlighting ultrasound
Area of Science:
- Pediatric endocrinology
- Medical imaging
- Ultrasound technology
Background:
- Thyroid gland volume and structure are crucial indicators of health.
- Establishing normal sonographic parameters in pediatric populations is essential for accurate diagnosis.
- Variations in thyroid ultrasound can signify underlying endocrine or developmental issues.
Purpose of the Study:
- To establish normal thyroid gland volume ranges using ultrasound in healthy children aged newborn to 17 years.
- To identify characteristic ultrasonic differences in pediatric thyroid conditions compared to normal glands.
- To assess the diagnostic value of thyroid sonography in childhood.
Main Methods:
- Prospective study involving 598 healthy children (newborn to 17 years).
- Thyroid gland examination using ultrasound.
- Measurement of thyroid gland volume.
- Comparison of ultrasonic structures between normal pediatric glands and those with specific conditions.
Main Results:
- Normal thyroid gland volumes were established: 1.1 cm³ in neonates, 2 cm³ in 4-year-olds, and 8.7 cm³ in schoolchildren.
- Distinct ultrasonic structural differences were observed in newborns, congenital hypothyroidism, median cervical cyst, autoimmune thyroiditis with diabetes, and adenoma.
- Thyroid sonography provided valuable diagnostic information in pediatric cases.
Conclusions:
- Ultrasound is a valuable tool for assessing thyroid gland volume and structure in children.
- Normal sonographic reference ranges are established for pediatric thyroid glands.
- Thyroid sonography effectively differentiates normal glands from those with various pathological conditions in childhood.
Abstract:
In a prospective study the thyroid glands of 598 healthy boys and girls (newborn to 17 years old) were examined by ultrasound. The volume of the normal gland was 1.1 cm3 in neonates, 2 cm3 in 4 year-old-children, and 8.7 cm3 in schoolchildren. The gland of a normal newborn, a girl with congenital hypothyroidism, a girl with inflammation of a median cervical cyst, a girl with insulin-dependent diabetes mellitus and autoimmune thyroiditis, and a girl with an adenoma all showed typical differences in ultrasonic structure from the normal adult gland. Sonography of the thyroid gland discloses valuable information, especially in childhood.
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