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Updated: Aug 24, 2026

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors
Published on: April 9, 2014
1st International Workshop on HIV Persistence during Therapy. St. Martin, December 10-12, 2003
1Essex Pharma GmbH, Tannenstrasse 15/15a, D-42653 Solingen, Germany. gudrun.tossing@essex.de
Abstract:
HIV-pathogenesis involves both pathogenic effects on some HIV infected cells and indirect effects on uninfected bystander cells. It has been self-evident for almost 20 years that reducing the amount of virus is beneficial to infected patients, as reduction in HIV-RNA viral load blocks direct as well as indirect pathogenic effects of HIV-1. However, eradication has not been achieved. As during suppressive HAART (highly active antiretroviral therapy) a great variety of cells can become HIV-reservoirs, they feature as numerous potential targets for new therapeutic approaches as for instance immune-based therapy.
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