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Relation between axial length of the eye and hypotensive effect of latanoprost in primary open angle glaucoma
1University of Alcalá, Hospital Oftalmológico Internacional de Madrid. esther-arranz@ole.com
Aims:
To study the effect of axial length on the hypotensive effect of latanoprost in primary open angle glaucoma (POAG) in a prospective, observational study.
Methods:
The authors measured axial length and baseline intraocular pressure (IOP) of 109 eyes with POAG, and then repeated the IOP measurements at 1, 3, and 6 months after starting treatment with latanoprost.
Results:
The mean IOP level was significantly lower in eyes with a shorter axial length compared with the eyes with a longer axial length both at 3 and 6 months of treatment (p = 0.03 and p = 0.04, respectively, ANOVA).
Conclusion:
The hypotensive effect resulting from treatment with latanoprost could be related to ocular axial length.
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