Evaluation and comparison of automated biopsy devices. Work in progress

Area of Science:

• Veterinary Medicine
• Medical Devices
• Surgical Technology

Background:

• Automated biopsy devices are increasingly used for tissue sampling in veterinary medicine.
• Ultrasound guidance enhances precision in organ biopsy procedures.
• Comparative studies are essential to evaluate the performance of different biopsy devices.

Purpose of the Study:

• To compare the performance of four automated biopsy devices (Bard Biopty, Bard Monopty, Microvasive ASAP 18, Medical Device Technologies Ultra-Cut) for liver and kidney sampling.
• To assess sample characteristics, tissue preservation, and organ trauma associated with each device.

Main Methods:

• Eight dogs underwent ultrasound-guided liver and kidney biopsies using four automated devices.
• A total of 96 liver and 96 kidney samples were collected.
• Sample length, weight, histological preservation, crush artifact, cellular integrity, and organ trauma were evaluated.

Main Results:

• No significant differences were observed in sample lengths or histological quality (preservation, crush artifact, glomeruli/lobules, portal triads) among the four devices.
• The Bard Monopty device produced significantly heavier kidney (30.8%) and liver (31.6%) samples compared to the others.
• Renal subcapsular hematomas were common, with no significant difference in renal trauma between devices. One instance of severe liver injury occurred.

Conclusions:

• All four automated biopsy devices are satisfactory for ultrasound-guided liver and kidney sampling in dogs.
• Device selection can be based on personal preference, as no significant differences in tissue quality or organ injury were found.
• The Bard Monopty device's tendency to yield heavier samples may be a consideration in device choice.