Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Carbaryl-A selective genotoxicant.

I S Grover1, S S Ladhar, S K Randhawa

  • 1School of Life Sciences, Guru Nanak Dev University, Amritsar-143005, India.

Environmental Pollution (Barking, Essex : 1987)
|January 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Influence of Long Term Application of Butachlor on its Dissipation and Harvest Residues in Soil and Rice.

Bulletin of environmental contamination and toxicology·2017
Same author

The genus Argemone : II. Cytogenetic relationships of A. ochroleuca ssp. ochroleuca (2n = 56) and some diploid (2n = 28) Argemone species.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2014
Same author

Antigenotoxic properties of Terminalia arjuna bark extracts.

Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer·2004
Same author

Antimutagenic potential of extracts isolated from Terminalia arjuna.

Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer·2001
Same author

Growth suppression of human transformed cells by treatment with bark extracts from a medicinal plant, Terminalia arjuna.

In vitro cellular & developmental biology. Animal·2001
Same author

Modulatory effects of a tannin fraction isolated from Terminalia arjuna on the genotoxicity of mutagens in Salmonella typhimurium.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association·2000
Same journal

Mineral dust deposition drives rare earth element accumulation in indoor dust and associated health risks in the Bayan Obo region.

Environmental pollution (Barking, Essex : 1987)·2026
Same journal

Spatial Variability and Pollutant-specific Mitigation Effects of an Urban Vegetated Park Observed with a High-density Air Quality Sensor Network.

Environmental pollution (Barking, Essex : 1987)·2026
Same journal

Sublethal effects of field-recommended glyphosate exposure on the predatory insect Arma chinensis: Growth inhibition and reproductive costs.

Environmental pollution (Barking, Essex : 1987)·2026
Same journal

Emission of Hazardous Air Pollutants in Solid Recovered Fuel (SRF) Industrial Boilers and Health Risk Assessment in the Vicinity.

Environmental pollution (Barking, Essex : 1987)·2026
Same journal

Developing a Global Integrated Environmental Quality Index for Public Health Research.

Environmental pollution (Barking, Essex : 1987)·2026
Same journal

Polymer-specific hazard, more than particle abundance, shapes microplastic ecological and dietary risk profiles in a tropical mangrove estuary.

Environmental pollution (Barking, Essex : 1987)·2026
See all related articles

Carbaryl, an insecticide, did not show mutagenic effects in Salmonella typhimurium strains. However, it induced chromosomal aberrations in Allium cepa root cells, indicating potential genotoxicity in plants.

Area of Science:

  • Environmental toxicology
  • Plant science
  • Genetics

Background:

  • Carbaryl is a widely used insecticide with known toxicological properties.
  • Assessing the mutagenic potential of pesticides is crucial for environmental and health safety.
  • Investigating genotoxicity across different biological systems is essential for comprehensive risk assessment.

Purpose of the Study:

  • To evaluate the mutagenic effects of carbaryl using bacterial assays.
  • To assess the in vivo chromosomal aberration potential of carbaryl in plant root meristems.
  • To compare the genotoxic responses of bacterial and plant systems to carbaryl.

Main Methods:

  • Histidine reversion assay in Salmonella typhimurium strains (TA98, TA1535, TA102) with and without S9 mix.

Related Experiment Videos

  • In vivo chromosomal aberration analysis in Allium cepa root meristems.
  • Recovery experiments involving transfer of treated Allium cepa bulbs to distilled water.

    • Main Results:

    • Carbaryl did not significantly increase histidine revertant frequency in any Salmonella typhimurium strain.
    • Carbaryl induced various chromosomal aberrations in Allium cepa, including c-mitosis, stickiness, breaks, and bridges.
    • Recovery was observed in the mitotic index and a reduction in chromosomal aberration frequency after transferring treated bulbs.

    Conclusions:

    • Carbaryl exhibits genotoxic effects in plant systems (Allium cepa) by inducing chromosomal aberrations.
    • Carbaryl does not appear to be mutagenic in the tested bacterial strains (Salmonella typhimurium).
    • Differences in metabolic activation between bacterial and plant systems may explain the contrasting results.