[Reinforcement anastomoses in the small intestine with fibrin glue (experimental study)]

In an experiment on baby pigs the authors tested the strength of an end-to-end anastomosis of the small intestine by atraumatic inverted silon stitches in one layer reinforced by a fibrin film along the circumference of the suture. Intraluminal pressure was increased 15 minutes after application of the glue and completion of the anastomosis. The differences in the strength of the simple suture and that reinforced by the fibrin coagulum are statistically significant. The fibrin-reinforced anastomosis is more resistant against increased intraluminal pressure. After resection of the damaged portion the passage was restored by a new anastomosis in one layer and reinforced by fibrin glue. Five minutes after the fibrin film had dried, the loop was returned into the peritoneal cavity. All experimental animals survived without damage for a period of six months. Histological examination of the preparation confirmed satisfactory healing by a smooth scar without reaction of the tissue to alien material.