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[Chronic gastritis from the aspect of a thrombohemorrhagic syndrome]

V V Chernin, V A Solov'ev, V A Tkachev

    Terapevticheskii Arkhiv
    |January 1, 1992
    PubMed

    Insights

    Chronic gastritis involves significant microcirculation and hemostasis changes, linked to a chronic recurrent thrombohemorrhagic syndrome. These alterations contribute to the disease

    Area of Science:

    • Gastroenterology
    • Hematology
    • Pathophysiology

    Background:

    • Chronic gastritis (CG) is a prevalent gastrointestinal condition.
    • Understanding its underlying pathophysiological mechanisms is crucial for effective management.

    Purpose of the Study:

    • To investigate the role of microcirculatory and hemostatic changes in the pathogenesis of chronic gastritis.
    • To explore the association between these changes and the chronic recurrent thrombohemorrhagic syndrome.

    Main Methods:

    • Examination of 148 patients diagnosed with chronic gastritis.
    • Assessment of microcirculation and hemostasis parameters.

    Main Results:

    • Chronic gastritis is associated with significant alterations in microcirculation and hemostasis.
    • These changes are part of a chronic recurrent thrombohemorrhagic syndrome.
    • Manifestations are more pronounced during disease exacerbation, erosive gastritis, diffuse atrophy, secretory insufficiency, and in long-standing disease (>10 years).

    Conclusions:

    • Microcirculatory and hemostatic disorders are integral to the pathogenesis of chronic gastritis.
    • These disorders contribute to the development of morphofunctional changes in the gastric mucosa.

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