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Exercise-induced changes in QT interval duration and dispersion in patients with isolated myocardial bridging
Irfan Barutcu1, Alpay Turan Sezgin, Hakan Gullu
1Kocatepe Heart Education and Research Hospital, Department of Cardiology, Afyon, Turkey. irfanbarutcu@yahoo.com
Insights
Myocardial bridging (MB) patients show increased QT dispersion after exercise, suggesting potential exercise-induced ischemia. This finding highlights MB as a factor in cardiovascular events.
Area of Science:
- Cardiology
- Electrophysiology
- Diagnostic Imaging
Background:
- Isolated myocardial bridging (MB) is often underestimated but linked to cardiovascular events.
- Assessing exercise-induced electrocardiographic (ECG) changes and arrhythmia susceptibility in MB patients is crucial.
Purpose of the Study:
- To evaluate exercise-induced ECG alterations in patients with myocardial bridging.
- To determine if myocardial bridging increases susceptibility to arrhythmias during exercise.
Main Methods:
- 21 patients with proven MB and 25 controls underwent a Bruce protocol exercise test.
- QT interval duration and dispersion were measured before and after exercise.
Main Results:
- Patients with MB showed a significant increase in QT dispersion (QTd) and corrected QT dispersion (QTcd) post-exercise.
- QT maximum and minimum durations did not significantly change in MB patients after exercise.
- Control group showed no significant changes in QT parameters after exercise.
Conclusions:
- Treadmill exercise testing significantly increases QT dispersion in patients with myocardial bridging.
- This observed increase in QT dispersion may stem from exercise-induced ischemia in the bridged artery territory.
- Myocardial bridging warrants further investigation regarding its association with cardiovascular events.
Background:
Isolated myocardial bridging (MB) often is considered to be an unimportant angiographic finding; however, its association with cardiovascular event has been shown. In this study we aimed to assess exercise-induced electrocardiographic (ECG) changes and susceptibility to arrhythmia in patients with MB.
Method:
21 consecutive patients who had angiographically proven MB (group I) and 25 subjects (group II) who had normal coronary arteries underwent exercise test using Bruce protocol. Before and after the exercise test the changes in QT interval duration and dispersion were compared.
Results:
Baseline characteristics of both groups were similar. Heart rate significantly increased after exercise test in both groups. In group I, after exercise mean QT(max) and QT(min) durations did not change significantly compared to baseline values, respectively. (QT(max): 411+/-20 vs. 421+/-18 ms, p>0.05 and QT(min): 380+/-12 vs. 378+/-10 ms, p>0.05). However, following exercise test QT dispersion (QT(d)) and corrected QT dispersion (QT(cd)) significantly increased when compared to baseline values, respectively. (34+/-13 vs. 66+/-14 ms, p<0.05 and 37+/-14 vs. 69+/-17 ms, p<0.05) On the other hand, in control group QT(max) and QT(min) durations, QT(c) and QT(cd) did not change significantly compared to baseline values, respectively. (QT(max): 408+/-18 vs. 412+/-17 ms, p>0.05 and QT(min): 390+/-11 vs. 387+/-10 ms, p>0.05; QT(d): 25+/-14 vs. 31+/-16 ms, p>0.05; QT(cd): 27+/-15 vs. 33+/-17 ms, p>0.05).
Conclusion:
Treadmill exercise test significantly increased QT dispersion in patients with MB. This increase may result from exercise-induced ischemia at the area perfused by bridged artery.
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