The fission yeast ptr1+ gene involved in nuclear mRNA export encodes a putative ubiquitin ligase

Tomoko Andoh1, Abul Kalam Azad, Asako Shigematsu

  • 1Department of Biological Science, Faculty of Science, Kumamoto University, Kurokami, Kumamoto 860-8555, Japan.

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Nuclear Export of mRNA

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Nuclear Export of mRNA02:31

Nuclear Export of mRNA

Before mRNAs are exported to the cytoplasm, it is crucial to check each mRNA for structural and functional integrity. Eukaryotic cells use several different mechanisms, collectively known as mRNA surveillance, to look for irregularities in mRNAs. Irregular or aberrant mRNA are rapidly degraded by various enzymes. If a defective mRNA escapes the surveillance, it would be translated into a protein which would either be non-functional or not function properly. One of the primary irregularities in...
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Export of Misfolded Proteins out of the ER

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Cotranslational Protein Translocation

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