Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

PET/CT: artifacts caused by bowel motion.

Yuji Nakamoto1, Bennett B Chin, Christian Cohade

  • 1Division of Nuclear Medicine, Johns Hopkins School of Medicine, Baltimore 21287-0817, USA.

Nuclear Medicine Communications
|April 20, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advances in Diabetes Medications and Patient Preparation for Oncologic FDG PET: <i>AJR</i> Expert Panel Narrative Review.

AJR. American journal of roentgenology·2026
Same author

Utility of Single-Shot Fast Spin-Echo T2-Weighted MRI With Deep Learning Reconstruction for Assessing Myometrial Invasion in Endometrial Cancer.

Journal of computer assisted tomography·2026
Same author

Fibroblast activation protein inhibitor-PET/CT in lung cancer: a prospective single-center study with histopathological correlation of fibroblast activation protein expression.

International journal of clinical oncology·2026
Same author

A narrative review: key evidence from meta-analyses in nuclear medicine.

Annals of nuclear medicine·2026
Same author

Enhanced tumor retention of the novel LAT1-targeting PET probe [<sup>18</sup>F]FAMT-OMe: A comparative study with [<sup>18</sup>F]FAMT in glioma mouse models.

Nuclear medicine and biology·2026
Same author

Single-Stage Lesion Identification in $^{68}$Ga-DOTATATE PET Images.

IEEE transactions on bio-medical engineering·2026

Bowel motion in PET/CT scans can cause differences in attenuation correction, leading to inaccurate standardized uptake values (SUVs). Overestimated uptake in CT corrected PET should not be mistaken for disease.

Area of Science:

  • Medical Imaging
  • Nuclear Medicine
  • Radiology

Background:

  • Positron Emission Tomography/Computed Tomography (PET/CT) systems utilize CT for attenuation correction.
  • Differences exist between CT-based and conventional transmission scan corrected PET images.
  • Bowel motion introduces variability in CT-based attenuation correction.

Purpose of the Study:

  • To investigate PET/CT image differences caused by bowel motion-induced attenuation variations.
  • To quantify the impact of bowel motion on standardized uptake values (SUVs).

Main Methods:

  • Twelve patients underwent PET/CT scans with both 68Ge transmission and CT attenuation correction.
  • Emission datasets were generated for CT corrected PET, Ge corrected PET, and difference images.

Related Experiment Videos

  • Mismatch regions and SUV discrepancies were analyzed.

    • Main Results:

    • 123 mismatched areas were identified between CT and Ge corrected PET.
    • 36 regions showed overestimation (Pattern A) and 87 showed underestimation (Pattern B) in CT corrected images.
    • Statistically significant differences in SUV values were observed between over- and underestimated regions.

    Conclusions:

    • Physiological bowel motion can lead to attenuation differences and affect SUV measurements in PET/CT.
    • Overestimation of fluorodeoxyglucose uptake due to motion artifacts should not be misdiagnosed as pathology.