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Monitoring the Reductive and Oxidative Half-Reactions of a Flavin-Dependent Monooxygenase using Stopped-Flow Spectrophotometry
12:08

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Aldose reductase structures: implications for mechanism and inhibition

O El-Kabbani1, F Ruiz, C Darmanin

  • 1Department of Medicinal Chemistry, Victorian College of Pharmacy, Monash University, Parkville Campus, 3052 Parkville, Victoria, Australia. ossama.el-kabbani@vcp.monash.edu.au

Cellular and Molecular Life Sciences : CMLS
|April 20, 2004
PubMed
Summary

Aldose reductase inhibitors (ARIs) show promise for diabetic complications but lack specificity. Understanding the enzyme

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