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Updated: Aug 24, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
Published on: January 29, 2018
[Physical exercise and bone development in chronically ill children]
Nathalie J Farpour-Lambert1, Laetitia Keller-Marchand, René Rizzoli
1Division d'endocrinologie et diabétologie pédiatriques Département de pédiatrie Hôpitaux Universitaires, Genève. nathalie.farpourlambert@hcuge.ch
Insights
Children with chronic diseases face higher risks of poor bone health. Exercise may improve bone mineral density in children with juvenile idiopathic arthritis and type 1 diabetes.
Area of Science:
- Pediatrics
- Orthopedics
- Endocrinology
Context:
- Children with chronic diseases often experience impaired bone development, increasing osteoporosis risk.
- Factors like delayed growth, low physical activity, and certain medications exacerbate bone health issues.
- The impact of physical activity on bone development in these children is not well understood.
Purpose:
- To investigate the relationship between physical fitness, muscle strength, and bone mineral density in children with juvenile idiopathic arthritis (JIA).
- To evaluate the effects of a moderate-impact exercise training program on bone mineral density in children with JIA and type 1 diabetes mellitus.
Summary:
- Preliminary findings indicate a positive correlation between physical fitness, muscle strength, and hip bone mineral density in children with JIA.
- Bone mineral density was found to be lower on the more affected side in children with JIA.
- Two randomized controlled trials are underway to assess exercise interventions for bone health in JIA and type 1 diabetes.
Impact:
- This research aims to establish the benefits of exercise for bone health in pediatric chronic disease populations.
- Findings could inform clinical guidelines for managing and preventing osteoporosis in children with chronic conditions.
- Understanding exercise's role can lead to targeted interventions to improve long-term bone health outcomes.
Abstract:
Children with chronic diseases are at increased risk of sub-optimal bone mineral acquisition and osteoporosis, especially those who have a growth and pubertal delay, reduced physical activity, inadequate nutrition, malabsorption or take medications which may influence bone development. Weight-bearing physical activity has a beneficial effect on bone development of healthy children but little is known in children with chronic diseases. Preliminary results of our cross-sectional study in children with juvenile idiopathic arthritis (JIA) suggest that hip bone mineral density is positively related with physical fitness and muscle strength and is reduced at the more affected side. We have initiated two randomized controlled trials to determine the effects of a moderate impact exercise training program on bone mineral density of children with JIA and type 1 diabetes mellitus.
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