Deep tendon reflexes, magnesium, and calcium: assessments and implications

Area of Science:

• Perinatology
• Clinical Pharmacology

Background:

• Magnesium sulfate is frequently used in perinatal care for seizure prevention (e.g., preeclampsia) and tocolysis.
• Both applications carry a risk of magnesium toxicity.
• Monitoring is crucial for patient safety.

Purpose of the Study:

• To highlight the role of deep tendon reflexes and clinical signs in managing magnesium infusions.
• To emphasize the importance of regular patient assessment for magnesium toxicity.
• To compare the utility of clinical signs versus serum levels in detecting magnesium toxicity.

Main Methods:

• Clinical observation of physical manifestations.
• Assessment of deep tendon reflexes.
• Correlation of clinical signs with magnesium infusion management.

Main Results:

• Deep tendon reflexes serve as a valuable tool for guiding magnesium infusion adjustments.
• Physical signs of toxicity can be more indicative of tissue magnesium levels than serum levels.
• Regular assessment is vital for identifying and managing toxicity.

Conclusions:

• Perinatal nurses, in conjunction with physicians, can effectively use deep tendon reflexes and clinical signs to manage magnesium infusions.
• Clinical assessment is a critical component of ensuring patient safety when administering magnesium sulfate.
• Proactive monitoring prevents adverse events associated with magnesium toxicity.