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Updated: Aug 24, 2026

Isolation of Leukocytes from Human Breast Milk for Use in an Antibody-dependent Cellular Phagocytosis Assay of HIV Targets
Published on: September 6, 2019
Breastfeeding and maternal HIV-1 disease progression and mortality
Gilda Sedgh1, Donna Spiegelman, Ulla Larsen
1Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.
Objective:
To examine the association between breastfeeding and disease progression among HIV-infected women in Dar es Salaam, Tanzania.
Design And Methods:
Cohort study design with Cox proportional hazards models.
Results:
The relative risk of death comparing women who recently had been breastfeeding to those who were not breastfeeding was 0.47 (95% confidence interval, 0.18-1.20). Neither breastfeeding status nor the duration of exclusive or partial breastfeeding was associated with HIV-1 disease progression, represented by death or development of a low CD4 cell count, anemia or excessive weight loss, in multivariate analyses. These associations remained insignificant when women with relatively low and high CD4 cell counts were analyzed separately.
Conclusion:
There is insufficient evidence to support the hypothesis that breastfeeding is detrimental to the health of HIV-infected women.
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