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Related Experiment Videos

Same-size donor corneas for myopic keratoconus.

Shigeto Shimmura1, Masako Ando, Misaki Ishioka

  • 1Department of Ophthalmology, Tokyo Dental College, Ichikawa, Japan. shimmura@tdc.ac.jp

Cornea
|April 21, 2004
PubMed
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Using same-size donor grafts for keratoconus patients with long visual axes is a safe and effective way to reduce myopia after penetrating keratoplasty (PKP). This study found it reduced postoperative myopia in patients with axial myopia.

Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Refractive Surgery

Background:

  • Keratoconus is a progressive thinning of the cornea, often leading to irregular astigmatism and myopia.
  • Penetrating keratoplasty (PKP) is a common surgical treatment for advanced keratoconus.
  • Graft size selection in PKP for keratoconus can influence refractive outcomes, particularly in myopic eyes.

Purpose of the Study:

  • To evaluate the efficacy of using same-size donor grafts in keratoconus patients with axial myopia.
  • To assess the impact of same-size donor grafts on postoperative spherical equivalent (SE) and visual acuity.
  • To determine the safety and complication rates associated with same-size donor graft PKP in this population.

Main Methods:

  • A prospective, noncomparative interventional case series included 142 eyes of 136 keratoconus patients.

Related Experiment Videos

  • Penetrating keratoplasty (PKP) was performed using a standardized technique.
  • Donor graft size was matched to the recipient eye's axial length (AXL): same-size for AXL > 24.50 mm, 0.25 mm oversized for AXL < 24.49 mm.

    • Main Results:

    • The average postoperative SE was -3.94 +/- 3.21 D, with average corrected visual acuity of 0.90.
    • Postoperative SE showed an inverse correlation with preoperative axial length (AXL).
    • Graft rejection occurred in 5.7% of eyes; 2 eyes required surgery for glaucoma.

    Conclusions:

    • Using same-size donor grafts in keratoconus patients with a long visual axis is safe and effective.
    • This technique successfully reduces postoperative myopia in patients undergoing PKP.
    • Same-size donor grafts are a viable option for managing refractive outcomes in keratoconus surgery.