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Updated: Aug 24, 2026

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
Published on: October 10, 2025
Vasculopathy in von Recklinghausen's neurofibromatosis--a diagnostic quandary
Gerlinde Obermoser1, Bettina G Zelger, Gunda Millonig
1Department of Dermatology, University Hospital of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.
Abstract:
Vasculopathy is a not well-described presentation of neurofibromatosis type 1 in the dermatologic literature. We report a fatal case of neurofibromatosis vasculopathy in a 28-year-old woman who presented with skin ulcers and livedo racemosa; extensive gastrointestinal ulcers; and infarction of the bowel, liver, and spleen. Being alert to this manifestation may avoid unnecessary delay in diagnosis and enable, whenever possible, appropriate therapy.
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