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Updated: Aug 24, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Persistent blue nevus simulating melanoma
Christine Muñoz1, Aida Quintero, Jorge L Sánchez
1Department of Dermatology, School of Medicine, University of Puerto Rico, San Juan, Puerto Rico 00936-5067.
Abstract:
We report a case of a persistent blue nevus that significantly extended beyond the scar of the original excision mimicking those clinical changes usually seen in melanoma. The histopathologic evaluation revealed a common blue nevus. The lesion was re-excised, and 10 months later a bluish macule appeared next to the surgical scar. This case of a persistent blue nevus with an unusual clinical presentation and a benign clinical course highlights the fact that the clinical markers commonly used to identify melanoma in pigmented lesions will not always accurately diagnose melanoma.
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