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[Value of a provocation test with diprafenone in patients with bifascicular block]
C Hief1, K Frohner, A Podczeck
1Ludwig-Boltzmann-Institut für Arrhythmieforschung, 3. Medizinische Abteilung, Wilhelminenspital, Wien.
Abstract:
The significance of provocative tests in patients with bifascicular block is not established. We studied 14 patients with bifascicular block, syncope and documented episodes of high degree AV-block. 1.5 mg/kg Diprafenon was given after a period of at last 12 hours 1:1 AV-conduction. Electrophysiologic evaluation was performed before and after diprafenon. AV-block III could be provoked in 1 of 14 patients with Diprafenon. Therefore a total AV block occurred in 7% of patients. The low sensitivity of provocative test with Diprafenon even in patients with documented high degree AV-block prevents its application in clinical practice.