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Plasminogen regulates pro-opiomelanocortin processing

N Wang1, L Zhang, L Miles

  • 1Joseph J. Jacobs Center for Thrombosis and Vascular Biology, Department of Molecular Cardiology, Cleveland Clinic Foundation, Lerner Research Institute, Cleveland, OH 44195, USA.

Journal of Thrombosis and Haemostasis : JTH
|April 22, 2004
PubMed
Summary

Plasminogen deficiency impairs the processing of stress-related hormones like beta-endorphin and alpha-melanocyte stimulating hormone. This hormonal imbalance affects normal brain function and stress responses in mice.

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