Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multi-layer plastic/glass microfluidic systems containing electrical and mechanical functionality.

Arum Han1, Olivia Wang, Mason Graff

  • 1School of Electrical & Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30332-0250, USA. gt0478a@prism.gatech.edu

Lab on a Chip
|April 22, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preventive Care Uptake and Long-Term Healthcare Use Among Children with Fetal Opioid Exposure in Ontario, Canada: A Population-Based Retrospective Cohort Study.

International journal of population data science·2026
Same author

PRISM: A unified platform for phage isolation and characterization from single-droplet microenvironments.

Science advances·2026
Same author

ALSUntangled #82: N-acetylcysteine.

Amyotrophic lateral sclerosis & frontotemporal degeneration·2026
Same author

Reducing Small Molecule Adsorption in a PDMS-Based Microphysiological System of the Female Reproductive Tract via Parylene-C Coating to Improve Mechanistic Studies.

ACS applied materials & interfaces·2026
Same author

Enhanced operation of female reproductive microphysiological system (MPS) for rapid mechanistic study.

Micro and nano systems letters·2026
Same author

ALSUntangled #81: Pyridostigmine (mestinon<sup>®</sup>).

Amyotrophic lateral sclerosis & frontotemporal degeneration·2025
Same journal

Controlled encapsulation and droplet size prediction in two-step microfluidic double emulsions.

Lab on a chip·2026
Same journal

A particulate blood-mimicking fluid with physiological biconcave geometry for microscale hemorheology.

Lab on a chip·2026
Same journal

Multicellular sensor arrays fabricated by capillary stamping for pattern-based odor discrimination.

Lab on a chip·2026
Same journal

A real-time microfluidic surveillance system for multiplex detection of heavy metal contamination in wastewater.

Lab on a chip·2026
Same journal

Vision-guided parallel manipulation of cells with optoelectronic tweezers.

Lab on a chip·2026
Same journal

Review of nanofluidic mass transport systems: engineering through physicochemical fields and interfacial properties.

Lab on a chip·2026
See all related articles

This study presents a novel method for creating integrated multi-layer microfluidic devices using glass and plastic. The approach successfully combines materials and incorporates electrical and mechanical functions for advanced micro-systems.

Area of Science:

  • Microfluidics
  • Materials Science
  • MEMS (Micro-Electro-Mechanical Systems)

Background:

  • Fabricating complex multi-layer microfluidic systems often involves challenges in material compatibility and integration of diverse functionalities.
  • Existing methods may struggle to seamlessly incorporate electrical and mechanical components within a single microfluidic device.

Purpose of the Study:

  • To develop and demonstrate an approach for fabricating integrated multi-layer microfluidic systems using a combination of glass and plastic materials.
  • To characterize the microfabrication technologies and the performance of the resulting systems.

Main Methods:

  • Combined conventional MEMS fabrication with plastic processing techniques: hot embossing, heat staking, injection molding, microstenciling of electrodes, and stereolithography.

Related Experiment Videos

  • Fabricated and characterized multi-layer plastic/glass microfluidic systems.
  • Integrated electrical components (electrodes) and mechanical functionalities (microactuators).
  • Main Results:

    • Successfully realized monolithic multi-layer microfluidic systems integrating multiple materials (glass and plastic).
    • Demonstrated the effective integration of electrical functionality throughout the microfluidic system.
    • Incorporated microactuators, such as micropumps and valves, and developed interconnect technology for fluid and electrical interfacing.

    Conclusions:

    • The presented approach offers a versatile solution for fabricating advanced multi-layer microfluidic devices.
    • The method enables seamless integration of materials, electrical components, and microactuators, paving the way for more sophisticated micro-systems.
    • This fabrication strategy facilitates robust interfacing between micro-scale systems and the macro world.