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Updated: Aug 24, 2026

Targeted Muscle Reinnervation: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain
Published on: March 8, 2024
Failure to diagnose pain of muscular origin leads to unnecessary surgery
1Norman Marcus Pain Institute, New York, New York 10016, USA.
Abstract:
Three patients who were scheduled for surgical procedures for a variety of diagnoses are presented. Each of the patients presented with pain that was interpreted as a result of an operable lesion. None of the patients was assessed for a possible muscular etiology of their pain prior to being evaluated at the author's pain center. In all three patients, muscles were identified that replicated their pain. Each patient received treatment to his or her pain-producing muscles. None of the contemplated surgeries was performed.
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