Related Experiment Video
Updated: Aug 24, 2026

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
Published on: October 14, 2021
Cutaneous T-cell lymphoma in a 21-year-old male with Wolf-Hirschhorn syndrome
Beau Batton1, Adoor Amanullah2, Charles Main2
1William Beaumont Hospital, Department of Pediatrics, Royal Oak, Michigan.
Abstract:
We describe a case of cutaneous T-cell lymphoma occurring in a 21-year-old male with Wolf-Hirschhorn syndrome (WHS) due to a chromosome 4p16.3 deletion. This is the first documented case report of malignancy occurring in an adult with WHS. We also review the literature regarding patients with WHS and the joint occurrence of malignancy and discuss genetic changes involving chromosome 4 which may have contributed to the genesis of our patient's lymphoma.