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Updated: Aug 24, 2026

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
Published on: September 7, 2022
[Peritonsillar abscess associated with infectious mononucleosis: retrospective study of three cases]
Akio Hatanaka1, Atsunobu Tsunoda, Hiromi Kanazawa
1Department of Otolaryngology, Asahi General Hospital, Asahi.
Abstract:
Three cases with infectious mononuculeosis associated with peritonsillar abscess were reviewed. The initial diagnoses in these three cases were tonsillitis or peritonsillitis. However, infectious mononucleosis was suspected because of an elevation in aminotransferases and was later confirmed by elevations in the titers of antibodies for Epstein-Barr virus. Peritonsillar abscesses developed and surgical drainage was performed in all three cases. The present study suggests a higher incidence of peritonsillar abscess in patients with infectious mononucleosis than previously expected.
Insights
Infectious mononucleosis can lead to peritonsillar abscesses, a complication not previously recognized. Early diagnosis of Epstein-Barr virus is crucial for managing these cases effectively.
Area of Science:
- Otolaryngology
- Infectious Diseases
- Virology
Background:
- Peritonsillar abscess is a known complication of tonsillitis.
- Infectious mononucleosis is caused by the Epstein-Barr virus (EBV).
Observation:
- Three cases of infectious mononucleosis presented with initial misdiagnoses of tonsillitis or peritonsillitis.
- Elevated aminotransferases prompted suspicion of infectious mononucleosis.
- Epstein-Barr virus antibody titers confirmed the diagnosis.
Findings:
- All three patients developed peritonsillar abscesses requiring surgical drainage.
- The study indicates a potentially higher incidence of peritonsillar abscess in infectious mononucleosis patients than previously reported.
Implications:
- This suggests that infectious mononucleosis should be considered in the differential diagnosis of peritonsillar abscess.
- Increased awareness may lead to earlier diagnosis and appropriate management of EBV-associated peritonsillar abscesses.
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Chronic Pharyngitis
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Viral Meningitis
Poliomyelitis
