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Intraocular penetration of rifampin in humans
W R Outman1, R E Levitz, D A Hill
1Department of Pharmacy Services, Hartford Hospital, Connecticut 06115.
Antimicrobial Agents and Chemotherapy
|July 1, 1992
Abstract:
The penetration of rifampin into human aqueous humor was determined in 15 patients undergoing elective cataract surgery. Between 0.9 and 5.5 h after administration of a single 600-mg oral dose, concentrations ranged from 6.0 to 21.5 mg/liter in serum and from less than 0.2 to 1.3 mg/liter in aqueous humor.