Related Experiment Videos
[Prophylaxis in prostatic surgery with aztreonam. Our experience].
J L Moyano Calvo1, R Arellano Gañán, A Sempere Gutiérrez
1Servicio de Urología, Hospital La Princesa, Universidad Autónoma, Madrid, España.
Archivos Espanoles De Urologia
|July 1, 1992
Summary
Aztreonam effectively prevents and treats urinary tract infections in prostate surgery patients. This monobactam antibiotic demonstrated utility in a study of 32 patients undergoing this common procedure.
Area of Science:
- Infectious Diseases
- Urology
- Pharmacology
Context:
- Prostate surgery is a common procedure with a risk of urinary tract infections (UTIs).
- Gram-negative aerobic bacteria are primary causative agents of UTIs.
- Antibiotic prophylaxis is crucial in preventing post-operative infections.
Purpose:
- To evaluate the efficacy of Aztreonam in prophylaxis and treatment of UTIs in patients undergoing prostate surgery.
- To assess the safety and effectiveness of a specific Aztreonam dosing regimen.
Summary:
- A study involving 32 patients undergoing prostate surgery administered 1 gm Aztreonam at induction and every 8 hours for a total of 3 gm.
- Urine cultures were obtained pre-operatively and 72 hours post-operatively.
- Twenty-eight patients experienced no complications with sterile or low-colony-count urine cultures. Two patients developed Staph. aureus wound infections, and one had Enterococci in their urine.
Impact:
- Aztreonam shows promise as a prophylactic and therapeutic agent for UTIs in the context of prostate surgery.
- The findings suggest Aztreonam's utility in managing infections associated with this surgical procedure.
- Further research may confirm Aztreonam's role in urological surgery protocols.