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Multiplex Immunohistochemical Analysis of the Spatial Immune Cell Landscape of the Tumor Microenvironment
Published on: August 18, 2023
[Are there new possibilities in immunomorphology?]
1Hisztopatológia KFT, Péc, 7608, Hungary. histopat@mail.datanet.hu
Immunomorphology, including immunohistochemistry and immunocytochemistry, forms a category of well known, reproducible, cost and environment saving immunodiagnostic methods based on immunological specificity. Both the accurate diagnosis and a better knowledge of biological parameters of diseases, especially of malignant tumors, result from the continual development of technologies and applications concerning at least 60 years of history of immunostaining. This review attempts to summarize the most important steps of development of immunomorphology.
Immunomorphology, including immunohistochemistry and immunocytochemistry, forms a category of well known, reproducible, cost and environment saving immunodiagnostic methods based on immunological specificity. Both the accurate diagnosis and a better knowledge of biological parameters of diseases, especially of malignant tumors, result from the continual development of technologies and applications concerning at least 60 years of history of immunostaining. This review attempts to summarize the most important steps of development of immunomorphology.

