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Measles surveillance in the United States: an overview
Dalya Guris1, Rafael Harpaz, Susan B Redd
1National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. dhm5@cdc.gov.
Abstract:
The elimination of endemic measles from the United States has been a national goal since the introduction of measles vaccine, and measles surveillance has been crucial to guide the elimination efforts. The United States surveillance system is geared towards detection of measles virus transmission, rapid discovery of measles outbreaks to facilitate outbreak control, and identification of risk factors for measles. The surveillance system is a passive reporting system that, when activated by a reported case of suspected measles, triggers a search for additional cases around the reported case. Cases are typically reported by health care providers or from schools and day care centers. The sensitivity of the system is increased through reporting and investigation of all suspected measles cases by means of an inclusive case definition (generalized maculopapular rash and fever), and the specificity is increased through laboratory testing for measles of all suspected cases.
Insights
The United States measles surveillance system detects virus transmission and outbreaks, aiding measles elimination efforts. It uses passive reporting, inclusive case definitions, and lab testing to ensure accurate case identification and control.
Area of Science:
- Public Health
- Epidemiology
- Infectious Disease Control
Background:
- Measles elimination is a national goal in the United States, pursued since the measles vaccine's introduction.
- Effective measles surveillance is critical for guiding and achieving elimination efforts.
Purpose of the Study:
- To describe the United States measles surveillance system's design and function.
- To highlight its role in detecting transmission, controlling outbreaks, and identifying risk factors.
Main Methods:
- A passive reporting system activated by suspected measles cases.
- Investigation of additional cases surrounding a reported event.
- Utilizes an inclusive case definition (fever and generalized rash) to enhance sensitivity.
- Employs laboratory testing for measles confirmation to increase specificity.
Main Results:
- The system is designed for detecting measles virus transmission.
- Facilitates rapid discovery and control of measles outbreaks.
- Aids in identifying risk factors associated with measles spread.
Conclusions:
- The described surveillance system effectively supports measles elimination goals.
- Its combination of passive reporting, broad case definition, and laboratory confirmation enhances accuracy and utility.
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