[Rare forms of myeloma disease]

Clinical forms of myelomic disease, which is not a rare hematological illness, pathogenetically related to IgG and IgA hyperproduction, have a well-known symptoms complex and therefore present no diagnostic difficulties, but plasmocytoma can run without a typical clinical picture. In 1-5% cases M-component is represented by IgD, in 18-20%--by light chains of immunoglobulins. Unsecreting myeloma has no M-component. Atypical are also solitary and extramedullary plasmocytomas. Whether atypical forms of myelomic disease exist or its variants, even rare, present with own typical clinical picture, is discussed.