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Related Experiment Videos

Hepatitis B immunization: cost calculation in a community-based study in India.

Mohit Sahni1, Kapil Jindal, Nalini Abraham

  • 1Department of Pediatrics, St. Stephen's Hospital, Tis Hazari, New Delhi 110 054.

Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology
|April 27, 2004
PubMed
Summary

Universal hepatitis B vaccination for newborns in India is not cost-beneficial. The expense per quality-adjusted life-year (QALY) saved exceeds the nation's per capita Gross National Product (GNP).

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Area of Science:

  • Public Health
  • Health Economics
  • Immunization Policy

Background:

  • Limited data exists on the cost-effectiveness of early hepatitis B vaccination in India, where most births occur at home.
  • This study addresses the need for policy planning regarding neonatal immunization strategies.

Purpose of the Study:

  • To evaluate the costs associated with a community-based program for vaccinating newborns against hepatitis B within 48 hours of birth in India.
  • To determine the cost-benefit and cost-utility of universal hepatitis B immunization.

Main Methods:

  • A 1-year community-based study in India involving HBsAg testing for mothers and selective/universal vaccination of newborns.
  • Calculation of costs for selective vaccination, nursing time, and national universal immunization.

Related Experiment Videos

  • Cost-benefit and cost-utility analysis (cost per QALY saved) with sensitivity testing.

    • Main Results:

    • Nationwide universal hepatitis B vaccination was estimated to cost Rs 48,000 per QALY saved.
    • This cost is double India's per capita GNP, increasing to Rs 260,000 when discounted at 3%.

    Conclusions:

    • Universal hepatitis B vaccination is not cost-beneficial in India.
    • The cost per life-year gained through universal vaccination exceeds India's per capita GNP, indicating a need for alternative strategies.