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In Vitro and In Vivo Models to Study Corneal Endothelial-mesenchymal Transition
Published on: August 20, 2016
Clinical responses of the corneal endothelium
William M Bourne1, Jay W McLaren
1Mayo Clinic, Department of Ophthalmology, 200 First Street SW, Rochester, MN 55905, USA. bourne@mayo.edu
Experimental Eye Research
|April 27, 2004
Abstract:
The corneal endothelium maintains corneal deturgescence and clarity by a pump-leak mechanism first described by David Maurice. This cell layer can be investigated clinically with specular microscopy, fluorophotometry, and pachymetry. We describe the clinical responses of the corneal endothelium to aging, drugs, glaucoma, contact lens wear, trauma, disease, and surgery.
