[Contribution of high pressure to pharmaceutical and medical science]

Y Rigaldie1, G Demazeau

  • 1LPCHP, Laboratoire de physico-chimie des hautes pressions (Interface hautes pressions ENSCPB-ICMCB), Ecole nationale supérieure de chimie et de physique de Bordeaux (ENSCPB), 16, avenue Pey Berland, F33608 Pessac Cedex.

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Pressure of Fluids01:14

Pressure of Fluids

There are many examples of pressure in fluids in everyday life, such as in relation to blood (high or low blood pressure) and in relation to weather (high- and low-pressure weather systems). A given force can have a significantly different effect, depending on the area over which the force is exerted. For instance, a force applied to an area of 1 mm2 has a pressure that is 100 times greater than the same force applied to an area of 1 cm2. That's why a sharp needle is able to poke through skin...
Fluid Pressure01:14

Fluid Pressure

In mechanical engineering, fluid pressure plays a critical role in designing systems that utilize liquid flow, such as hydraulic systems, pumps, and valves. When designing these systems, engineers must ensure they can withstand the forces created by fluid pressure to avoid damage or failure.
According to Pascal's law, a fluid at rest will generate equal pressure in all directions. This pressure is measured as a force per unit area, and its magnitude depends on the fluid's specific weight or...
Bernoulli's Principle: Applications01:17

Bernoulli's Principle: Applications

There are many devices and situations in which fluid flows at a constant height and so can be analyzed using Bernoulli's principle. These devices include, but are not limited to, entrainment devices and fluid flow measuring devices.
Entrainment devices use a high fluid speed to create low pressures and, thus, entrain one fluid into another. Some examples of these devices are given below:
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Pressure Relationships in Thoracic Cavity

Breathing, otherwise known as pulmonary ventilation, is the process of air movement into and out of the lungs. The main mechanisms propelling pulmonary ventilation are atmospheric pressure (Patm), intra-pulmonary (Ppul ) or intra-alveolar pressure (Palv) within the alveoli, and intrapleural pressure (Pip) within the pleural cavity.
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Physical Principles Governing Gas Exchange01:16

Physical Principles Governing Gas Exchange

Gas behavior plays a vital role in understanding bodily processes such as external and internal respiration. External respiration involves the diffusion of oxygen into the blood and carbon dioxide out of it in the lungs. In contrast, internal respiration happens in body tissues, where these gases move in opposite directions.
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The behavior of gases is guided by Dalton's Law of partial pressures and Henry's Law.
Dalton's Law asserts that the total pressure exerted by...
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.