Metastatic epithelioid angiosarcoma of the heart in peritoneal fluid

Anjali Saqi1, Risha B Ramdall, Diane Hamele-Bena

  • 1Department of Surgical Pathology, New York Presbyterian Hospital, Columbia Presbyterian Medical Center, New York, New York 10032, USA. aas177@columbia.edu

Insights

Cardiac epithelioid angiosarcoma can metastasize to peritoneal fluid, a rare finding in exfoliative cytology. This case highlights the diagnostic potential of cytology for metastatic cardiac tumors.

Area of Science:

  • Oncology
  • Cytopathology
  • Cardiovascular Pathology

Background:

  • Angiosarcoma is the most frequent malignant heart neoplasm.
  • Recurrent pericardial effusions are a common sign of cardiac angiosarcomas.
  • Metastatic disease diagnosis in effusions is typically histological.

Observation:

  • Few cases of cardiac angiosarcoma metastasis diagnosed via exfoliative cytology exist.
  • This study details a rare instance of metastatic cardiac epithelioid angiosarcoma.
  • The metastasis was identified in peritoneal fluid.

Findings:

  • Exfoliative cytology can detect metastatic cardiac epithelioid angiosarcoma.
  • Peritoneal fluid cytology is a viable method for diagnosing this rare metastasis.
  • Histological confirmation is standard, but cytological diagnosis is possible.

Implications:

  • This case expands the understanding of angiosarcoma metastasis detection.
  • Cytopathology may offer an alternative diagnostic route for cardiac tumors.
  • Further research into cytological diagnosis of rare metastatic cancers is warranted.