Related Experiment Videos
[Effect of insulin-like growth factor I (IGF-I) on Sertoli cell metabolism in the pubescent rat]
M Prati1, S Palmero, P De Marco
1Istituto di Fisiologia Generale, Università di Genova.
Bollettino Della Societa Italiana Di Biologia Sperimentale
|February 1, 1992
Abstract:
The influence of Insulin-like Growth Factor I (IGF-I) on some metabolic functions of Sertoli cells from peripubertal rats was investigated. Sertoli cells were isolated from the testes of 24-day-old animals and cultured at 32 degrees C in Eagle's MEM with or without 1 nM IGF-I. Sertoli cells cultured in the presence of IGF-I showed increased nuclear RNA polymerase activity (+80%) and augmented protein synthesis (+50%).